Local Mutational Pressures in Genomes of Zaire Ebolavirus and Marburg Virus
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چکیده
منابع مشابه
Local Mutational Pressures in Genomes of Zaire Ebolavirus and Marburg Virus
Heterogeneities in nucleotide content distribution along the length of Zaire ebolavirus and Marburg virus genomes have been analyzed. Results showed that there is asymmetric mutational A-pressure in the majority of Zaire ebolavirus genes; there is mutational AC-pressure in the coding region of the matrix protein VP40, probably, caused by its high expression at the end of the infection process; ...
متن کاملReplication, pathogenicity, shedding, and transmission of Zaire ebolavirus in pigs.
UNLABELLED (See the editorial commentary by Bausch, on pages 179-81.) BACKGROUND Reston ebolavirus was recently detected in pigs in the Philippines. Specific antibodies were found in pig farmers, indicating exposure to the virus. This important observation raises the possibility that pigs may be susceptible to Ebola virus infection, including from other species, such as Zaire ebolavirus (ZEBO...
متن کاملEbolavirus and Marburgvirus Infections Ebola and Marburg Virus Disease, Ebola and Marburg Hemorrhagic Fever, African Hemorrhagic Fever
Ebolaviruses and marburgviruses are incompletely understood pathogens that cause severe, often fatal, illnesses in humans and non-human primates. These diseases have been known as Ebola and Marburg hemorrhagic fevers, respectively, after the most dramatic symptoms in severe cases. The names “Ebola virus disease” or Marburg virus disease” are now preferred by the World Health Organization (WHO) ...
متن کاملEbolavirus and Marburgvirus Infections Ebola and Marburg Virus Disease, Ebola and Marburg Hemorrhagic Fever, African Hemorrhagic Fever
Ebolaviruses and marburgviruses are incompletely understood pathogens that cause severe, often fatal, illnesses in humans and non-human primates. These diseases have been known as Ebola and Marburg hemorrhagic fevers, respectively, after the most dramatic symptoms in severe cases. The names “Ebola virus disease” or Marburg virus disease” are now preferred by the World Health Organization (WHO) ...
متن کاملUse of Postexposure Prophylaxis After Occupational Exposure to Zaire ebolavirus.
From September 2014 to April 2015, 6 persons who had occupational exposures to Zaire ebolavirus in West Africa received investigational agent rVSV-ZEBOV or TKM-100802 for postexposure prophylaxis and were monitored in the United States. All patients experienced self-limited symptoms after postexposure prophylaxis; none developed Ebola virus disease.
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ژورنال
عنوان ژورنال: Advances in Bioinformatics
سال: 2015
ISSN: 1687-8027,1687-8035
DOI: 10.1155/2015/678587